There are tuning options that can be done within the server itself as I think that is more of what you are after. That is something that we would rather not openly discuss in terms of tuning as it is a service that we will be providing either today or tomorrow. The TuneUp form will be up and you can request an official tune-up through there. I will make an announcement about it today when I get back from my meeting.
As per the OS. My go-to is Ubuntu 16.04. It's pretty much the basis for which I personally work my end of development for QuickBox on and run most of my test... so naturally, I would say run with it.